28.03.2023 - 08:43

Which one the following statements about HIV is false? A) long term nonprogessors lack CD4 molecules B) Bone marrow can be a reservoir for future infection C) HIV can be transmitted by cell to cell contact D) viral infection of TH cells results in sig

Question:

Which one the following statements about HIV is false?

A) long term nonprogessors lack CD4 molecules

B) Bone marrow can be a reservoir for future infection

C) HIV can be transmitted by cell to cell contact

D) viral infection of TH cells results in signs elsewhere in patient

E) CD8+ T cells decrease the viral load

Answers (1)
  • Himalaya
    April 4, 2023 в 09:32

    The false statement about HIV among the options is "A) long term nonprogressors lack CD4 molecules."

    Long-term nonprogressors are individuals who remain asymptomatic for an extended period of time despite being HIV positive. These individuals have lower viral loads and higher CD4+ T-cell counts compared to those who progress to AIDS.

    CD4+ T-cells are the primary target of HIV, and the virus infects and destroys these cells, leading to immunodeficiency. Therefore, it is unlikely that long-term nonprogressors would lack CD4 molecules. In fact, they have functional CD4+ T-cells that can control viral replication.

    Option B is true because bone marrow can act as a reservoir for HIV infection. The virus can remain dormant in the bone marrow and reactivate later, leading to a resurgence of the infection.

    Option C is also true because HIV can be transmitted through direct cell-to-cell contact between infected and uninfected cells.

    Option D is also true because viral infection of TH cells (CD4+ T-cells) can result in symptoms elsewhere in the patient due to the role of these cells in the immune system.

    Option E is true because CD8+ T-cells can recognize and kill HIV-infected cells, leading to a decrease in viral load.

    In summary, the false statement among the given options is A) long-term nonprogressors lack CD4 molecules.

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